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Welcome to the iSSB website

 Synthetic Biology (SynBio) was defined by ERASynBio as " the engineering of biology: the deliberate (re)design and construction of novel biological and biologically based parts, devices and systems to perform new functions for useful purposes, that draws on principles elucidated from biology and engineering."

Its industrial applications lie in the fields of environment, healthcare, materials and energy.

The Institute of Systems & Synthetic Biology (iSSB) belongs to the UMR 8030, a mixed research unit of University of Évry-Val-d'Essonne, University Paris-Saclay, CEA and CNRS. It is supported by Genopole.

It includes four teams active in the fields of xeno-nucleic acids and synthetic genomics, and of synthetic biochemical circuits. Their acronyms are Xenome, ASG, SysFate and Bio-Retrosynth.

iSSB represents the academic core of a local SynBio "ecosystem" comprising in addition a master degree (mSSB), an iGEM team (iGEM Evry), an annual School (aSSB), a few small companies, and a technological platform (abSYNTH).

Download iSSB flyer here.

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yeast image: Col Ford & Natasha de Vere

Location - contact


5 rue Henri Desbruères
Genopole Campus 1, Bât. 6

contact (at)

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37


To visit us, please follow Genopole access indications.  Once on Genopole campus 1, iSSB is located on the first floor of Building 6, which is the first building to your left as you cross the pedestrian gate, or to your right as you cross the car gate.


Longitude: E 2° 27' 4''
Latitude: N 48° 37' 7''



   Congratulations to the iGEM-Evry 2018 team that was nominated for the "best composite part" price, and that won a Gold Medal at the final world iGEM jamboree. To follow their work, please visit their wiki.


 The annual spring School on advances in Systems and Synthetic Biology (aSSB) becomes an autumn School, on November 18-22, 2019.

 iSSB is pleased to announce the creation of the spin-off Synovance, founded by two former iSSB researchers.

 The spin-off of iSSB Inovactis, founded by two former mSSB students, won the national competition I-Lab 2017 organized each year by the Ministry of Higher Education and Research to encourage the most innovative technologies.

  Based on publications in synthetic biology, an independent study (Nov 2015) found that iSSB ranks 3rd lab in Europe and 9th in the world, despite a comparatively small size.