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Imperatively, such components should be completely hazardless for their surrounding by their inability to genetically spread into existing ecosystems. As the natural genetic code for all life on our planet is solely recognized in the form of DNA and RNA polymers, a robust approach is being development of a truly orthogonal nucleic acid which is chemically distinct from DNA and RNA, but which can harbour structural and/or sequence information that is essential for the viability and phenotype of the cell. Obviously, such a “xeno”-nucleic acid (XNA) will be genetically inert, unless it can be accommodated by artificially evolved enzymes and synthesized from its xeno-nucleotide (XN) precursors. The latter, however, are not present in nature and need to be chemically synthesized and explicitly provided to the cell.

Location - contact

University of Evry-Val-d'Essonne

5 rue Henri Desbruères
Genopole Campus 1, Bât. 6

contact (at)

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37

To come, please follow Genopole access indications.

On the site, iSSB is located at 1st floor of Genavenir 6 building placed on your left (if you come by pedestrian entry) or on your right (if your come by vehicle entry).


Longitude: E 2° 27' 4''
Latitude: N 48° 37' 7''




  Thematic Research School "advances in Systems & Synthetic Biology" - aSSB-Evry'16. March 21-25, 2016

Mohamed Elati is one of the winners of the national call for proposal ITMO Cancer Aviesan-INSERM "Systems Biology and cancer".

logo 24Hchrono Sept. 5, 2015: Julie Zaworski, CIFRE PhD student at iSSB and Deinove, has won the national competition « 24 H chrono de l’entrepreneuriat » organized by the « Association Nationale de la Recherche et de la Technologie » (ANRT) . See details

igem-Evry-2015The iGEM-Evry-2015 team launched by mSSB students and hosted by iSSB received a Silver Medal at the World Championship. The team engineered innovative and promising new biological systems for modulating the immune system.

To learn about former iGEM-Evry teams, please visit our iGEM webpage.