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Imperatively, such components should be completely hazardless for their surrounding by their inability to genetically spread into existing ecosystems. As the natural genetic code for all life on our planet is solely recognized in the form of DNA and RNA polymers, a robust approach is being development of a truly orthogonal nucleic acid which is chemically distinct from DNA and RNA, but which can harbour structural and/or sequence information that is essential for the viability and phenotype of the cell. Obviously, such a “xeno”-nucleic acid (XNA) will be genetically inert, unless it can be accommodated by artificially evolved enzymes and synthesized from its xeno-nucleotide (XN) precursors. The latter, however, are not present in nature and need to be chemically synthesized and explicitly provided to the cell.


University of Evry-Val-d'Essonne

5 rue Henri Desbruères
Genopole Campus 1, Bât. 6

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37

To come, please follow Genopole access indications.

On the site, iSSB is located at 1st floor of Genavenir 6 building placed on your left (if you come by pedestrian entry) or on your right (if your come by vehicle entry).


Longitude: E  2° 27' 4''
Latitude: N 48° 37' 7''




IronLogo.jpg * The iGEM-Evry 2013 team: "human practice" price, gold medal at the European final. It was one of the 2 French teams selected for the world final in Boston.

copy_of_IFrog.jpg *  iGEM-Evry-2012 team: two prices (best model, best human practices), gold medal at the European jamboree, selection for the world final.