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Metamorphosys

Leader: Nicolas Pollet.

This team studies anura amphibian genome Xenopus tropicalis through 3 thematics: (i) genome structure, by characterizing the different DNA transposons families in xenopes and by using them in genome engineering experiment; (ii) genome expression, by characterizing transcriptomes during ontogenesis (premature development and metamorphosys); (iii) genomes evolution, by analyzing the evolution of transposons and regulator genes from ontogenesis.

Our group is interested in systems biology and genomics. Our project within the institute is to explore the fundamentals of genome structure and expression. Moreover we provide molecular genetics, transgenesis, transcriptomics and bioinformatic tools to study an easily amenable animal model. We study the genome of an anuran amphibian (a frog) named Xenopus tropicalis through three topics: genome structure, by the characterisation of X. tropicalis genome, including different families of mobile DNA (transposons) and using these transposons as genome engineering tools. We work on the improvement of the genome sequence and of its annotation. genome expression, by the characterisation of transcriptomes throughout ontogenesis (embryonic development and metamorphosis). We develop a collection of full-length cDNA sequences, and explore temporal and spatial restricted expression pattern to infer transcriptional networks. genome evolution, by the analysis of transposons evolution and of selected regulatory genes involved in ontogenesis. Detailed information can be found in the group website: http://indigene.issb.genopole.fr

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iSSB - CNRS FRE3561
University of Evry-Val-d'Essonne

5 rue Henri Desbruères
Genopole Campus 1, Bât. 6
F-91030 ÉVRY CEDEX, FRANCE

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37

To come, please follow Genopole access indications.

On the site, iSSB is located at 1st floor of Genavenir 6 building placed on your left (if you come by pedestrian entry) or on your right (if your come by vehicle entry).

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Longitude: E  2° 27' 4''
Latitude:  N 48° 37' 7''

News

Prestigious ERC advanced grant awarded to researchers of the iSSB Xenome team

* Dr. Alfonso Jaramillo wins the 3d prize in the synthetic biology Gen9-prize 2012 contest

* L'équipe iGEM-Evry recrute ! / the iGEM-Evry team is recruiting!

The iGEM-Evry-2012 team has won two prices (best model, best human practices) and got a gold medal at the European jamboree. It was selected for the world championship in Boston.

* Press file on Synthetic Biology
To learn more about Synthetic Biology: its origins, applications and potential, the biotech companies and the laboratories on the Genopole biopark working in this field.

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Metamorphosys