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2007

  1. Rodrigo G, Jaramillo A.  Computational design of digital and memory biological devices. Systems and Synthetic Biology, 2007, 1:183-195.
  2. Rodrigo G, Carrera J, Jaramillo A.  Asmparts: Assembly of biological model parts. Systems and Synthetic Biology, 2007, 1:167-170.
  3. Rodrigo G, Carrera J, Jaramillo A.  Genetdes: automatic design of transcriptional networks. Bioinformatics, 2007, 23(14):1857-1858.
  4. Rodrigo G, Carrera J, Jaramillo A. Evolutionary mechanisms of circadian clocks. Cent. Eur. J. Biol. 2007, 2:233-253.
  5. Rodrigo G, Montagud A, Aparici A, Aroca MC, Baguena B, Carrera J, Edo C, Fernandez-de-Cordoba P, Ferrando A, Fuertes G, Gimenez D, Mata C, Medrano JV, Navarrete C, Navarro E, Salgado J, Tortosa P, Urchueguia J, Jaramillo A.  Vanillin Cell Sensor. IET Synthetic Biology, 2007, 1:74-78.
  6. Norris V, Hunding A, Képès F, Lancet D, Minsky A, Raine D, Root-Bernstein R, Sriram K.  Question 7: the first units of life were not simple cells. Orig. Life Evol. Biosph.  2007, 37:429-443.
  7. Sriram K, Bernot G, Képès F.  A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle. IET Systems Biology, 2007, 1:326-341.
  8. Yartseva A, Devillers R, Klaudel H, Képès F.  From MIN model to ordinary differential equations. J. of Integrative Bioinformatics, 2007, 4:61.
  9. Yartseva A, Klaudel H, Devillers R, Képès F.  Incremental and unifying modelling formalism for biological interaction networks. BMC Bioinformatics, 2007, 8:433.
  10. Bronchain O, Pollet N, Ymlahi-Ouazzani Q, Dhorne-Pollet S, Helbling JC, Lecarpentier JE, Percheron K, Wegnez M.  The Olig family: phylogenetic analysis and early gene expression in Xenopus tropicalis. Development, Genes and Evolution, 2007, 217:485-497.
  11. Fierro AC, Thuret R, Coen L, Perron M, Demeneix BA, Wegnez M, Gyapay G, Weissenbach J, Wincker P, Mazabraud A, Pollet N.  Exploring the nervous system transcriptomes during embryogenesis and metamorphosis in Xenopus tropicalis using EST analysis. BMC Genomics, 2007, 8:118.
  12. Du Pasquier D, Chesneau A, Ymlahi-Ouazzani Q, Boistel R, Pollet N, Ballagny C, Sachs LM, Demeneix B, Mazabraud A.  TBid mediated Activation of the Mitochondrial Death Pathway leads to Genetic Ablation of the lens in Xenopus laevis. Genesis, 2007, 45:1-10.
  13. Troncale S, Thuret R, Ben C, Pollet N, Comet JP, Bernot G.  Modelling of the TH-dependent regulation of tadpole tail resorption. J. of Biol. Phys. Chem. 2007, 7:45-50.
  14. Vörbruggen H, Lagoja I, Herdewijn P.  Synthesis of ribonucleosides by condensation using trimethylsilyl triflate. Curr. Protoc. Nucleic Acid Chem. 2007, 1.13.1-1.13.16.
  15. Mikhailov SN, Efimtseva EV, Rodionov AA, Bobkov GV, Kulikova IV, Herdewijn P.
    Synthesis of 2’-O-β-D-ribofuranosyl nucleosides. Curr. Protoc. Nucleic Acid Chem. 2007, 1.14.1-1.14.19.
  16. Lambertucci C, Schepers G, Cristalli G, Herdewijn P, Van Aerschot A.  Synthesis and evaluation of hexitol nucleoside congeners as ambiguous nucleosides. Tetrahedron  Lett. 2007, 48:2143-2145.
  17. Fisher M, Abramov M, Van Aerschot A, Xu D, Juliano R, Herdewijn P.  Inhibition of MDR1 expression with altritol modified siRNA. Nucleic Acids Res. 2007, 35:1064-1074.
  18. Herdewijn P, Juliano R.  Nucleic acids with a six-membered carbohydrate mimic and RNA interference. Blood Cells, Mol. Dis. 2007, 38:100-101.
  19. Viña D, Wu T, Renders M, Laflamme G, Herdewijn P.  Synthesis of 3’-O phosphonomethyl nucleosides with adenine base moiety. Tetrahedron, 2007, 63:2634-2646.
  20. Nauwelaerts K, Lescrinier E, Herdewijn P.  Structure of α-homo DNA:RNA duplex and the function of twist and slide to catalogue nucleic acids duplexes. Chem. Eur. J. 2007, 13:90-98.
  21. Renders M, Emmerechts G, Rozenski J, Krecmerová M, Holý A, Herdewijn P.  Enzymatic synthesis of phosphonomethyl oligonucleotides by therminator polymerase. Angewandte Chem. Int. Ed. 2007, 46:2501-2504.
  22. Nauwelaerts K, Fisher M, Froeyen M, Lescrinier E, Van Aerschot A, Xu DG, De Long R, Kang H, Juliano RL, Herdewijn P.  Structural characterization and biological evaluation of small interfering RNAs containing cyclohexenyl nucleosides. J. Am. Chem.Soc. 2007, 129:9340-9348.
  23. Timofeev E, Mikhailov S, Zuev A, Efimtseva E, Somers R, Herdewijn P, Lemaitre M.
    Oligodeoxynucleotides containing N1-Me deoxyadenosine and their Dimroth rearrangement. Helv. Chim. Acta, 2007, 90:928-937.
  24. Zhou D, Froeyen M, Rozenski J, Van Aerschot A, Herdewijn P.  Chemical etiology of nucleic acids: aminopropyl nucleic acids. Chem. Biodiv. 2007, 4:740-761.
  25. Marchand A, Marchand D, Busson R, Marlière P, Herdewijn P.  Synthesis of a Pyridoxine–Peptide Based Delivery System for Nucleotides. Chem. Biodiv. 2007, 4:1450-1465.
  26. Horvath A, Ruttens B, Herdewijn P.  Stereoselective synthesis of (-)ara-cyclohexenyladenine. Tetrahedron Lett. 2007, 48:3621-3623.
  27. Lagoja I, Herdewijn P.  Preparation of guanine and diaminopurine from biuret. Chem. Biodiv. 2007, 4:818-822.
  28. Adelfinskaya O, Herdewijn P.  Amino Acid Phosphoramidate Nucleotides as Alternative Substrates for HIV-1 Reverse Trancriptase. Angewandte Chem. Int. Ed. 2007, 46:4365-4368.
  29. Mikhailov SN, Bobkov GV, Brilliantov KV, Rozenski J, Van Aerschot A, Herdewijn P, Fisher MH, Juliano RL.  2’-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26:1509-1512.
  30. Margineanu A, De Feyter S, Melnikov S, Marchand D, Van Aerschot A, Herdewijn P, Habuchi S, De Schryver FC, Hofkens J.  Complexation of lipofectamine and cholesterol-modified DNA sequences studied by single molecule fluorescence techniques. Biomacromolecules. 2007, 8:3382-3392.
  31. Froeyen M, Morvan F, Vasseur JJ, Nielsen P, Van Aerschot A, Rosemeyer H, Herdewijn P.  Conformational and chiral selection of oligonucleotides. Chem. Biodiv. 2007, 4:803-817.
  32. Emmerechts G, Barbé S, Herdewijn P, Anné J, Rozenski J.  Post-transcriptional modification mapping in the clostridium actobutylicum 16S rRNA by masspectrometry and reversed transcriptase assays. Nucleic Acids Res. 2007, 35:3494-3503.
  33. Goulioukina N, Wehbe J, Marchand D, Busson R, Lescrinier E, Heindl D, Herdewijn P.  Synthesis of NAD analogues with a sugar modified nicotinamide moiety. Helv. Chim. Acta, 2007, 90:1266-1278.
  34. Paeshuyse J, Chezal JM, Froeyen M, Leyssen P, Dutartre H, Vrancken R, Canard B, Letellier C, Li T, Mittendorfer H, Koenen F, Kerkhofs P, De Clercq E, Herdewijn P, Puerstinger G, Gueiffier A, Chavignon O, Teulade JC, Neyts J. The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication. J. Virol. 2007, 81:11046-11053.
  35. Stevens M, Balzarini J, Lagoja I, Noppen B, François K, Van Aerschot A, Herdewijn P, De Clercq E, Pannecouque C.  Inhibition of human immunodeficiency virus type 1 transcription by N-amino imidazole derivatives. Virology, 2007, 365:220-237.
  36. Lagoja I, Herdewijn P.  Use of RNA in drug design. Expert Opinion on Drug Discovery, 2007, 2:889-903. 
  37. Novoa de Armas H, Doboszewski B, Herdewijn P, Blaton N.  3-Deoxy-1,2-O-isopropylidene-3-C-methyl-5-O-(p-tolylsulfonyl)-D-ribofuranose. Acta Crystallographica, 2007, E63, 2678-2680.
  38. Abramov M, Herdewijn P.  Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis. Curr. Protoc. Nucleic Acids Chem. 2007, 1.18.1-1.18.21.
  39. Adelfinskaya O, Terrazas M, Froeyen M, Marlière P, Nauwelaerts K, Herdewijn P.  Polymerase-catalyzed synthesis of DNA from phosphoramidate conjugates of deoxynucleotides and amino acids. Nucleic Acids Res., 2007, 35:5060-5072.
  40. Rosemeyer H, Stürenberg EM, Herdewijn P.  Nucleolipids as potential organogelators. Nucleosides Nucleotides Nucleic Acids, 2007, 26:995-999.
  41. Voight-Goffmann F, Hengesbach M, Kobitski AY, Van Aerschot A, Herdewijn P, Nienhaus GU, Helm M.  A methyl group controls conformational equilibrium in human tRNALys. J. Am. Chem. Soc., 2007, 129:13382-13383.
  42. Gaucher SP, Morrow JA, Faulon JL.  Use of a Designed Peptide Array to Infer Dissociation Trends for Non-Tryptic Peptides in Quadrupole Ion Trap and Quadrupole Time of Flight Mass Spectrometry. Analytical Chemistry, 2007, 79:7822-7830.
  43. Gray GA, Williams PJ, Brown WM, Faulon JL, Sale K.  Disparate Data Fusion for Protein Phosphorylation Prediction”, Annals of Operations Research Special Volume on Data Mining, 2007.
  44. Zhang Z, Martino A, Faulon JL.  Global analysis of IL-2 responsive genes in murine T Cell. J. of Interferon & Cytokine Res., 2007, 27:991-995.
  45. Joo J, Plimpton S, Martin S, Swiler L, Slepoy A, Faulon JL.  Sensitivity analysis of computational model of the NF-κB-IκB-A20 signal transduction network. Annals of NY Academy of Sciences, 2007, 1115:221-239.
  46. Oprea T, Tropsha A, Faulon JL, Rintoul MD.  Systems Chemical Biology. Nature Chem. Biol., 2007, 3:447-450.
  47. Martin S, Zhang Z, Martino A, Faulon JL.  Boolean Dynamics of Genetic Regulatory Networks Inferred from Microarray Time Series Data. Bioinformatics, 2007, 23:866-874.
Location

iSSB - CNRS FRE3561
University of Evry-Val-d'Essonne

5 rue Henri Desbruères
Genopole Campus 1, Bât. 6
F-91030 ÉVRY CEDEX, FRANCE

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37

To come, please follow Genopole access indications.

On the site, iSSB is located at 1st floor of Genavenir 6 building placed on your left (if you come by pedestrian entry) or on your right (if your come by vehicle entry).

GPS

Longitude: E  2° 27' 4''
Latitude: N 48° 37' 7''

 

iSSBbuildingsmall.jpg

News

    Research Thematic School on advances in Systems & Synthetic Biology, March 23-27, 2015, in Strasbourg.

    Abolislogo.jpg iSSB is pleased to announce the creation of the spin-off Abolis . Abolis has already been awarded at two competitions: it is finalist at the 2030 World Innovation Challenge, and received a special prize at the Genopole's White Technologies competition.

    iSSB has received the Genopole award for Research Innovation, which rewards Genopole players achieving major scientific advances. This price has been awarded during the Genopole 15th anniversary day, after selection by an external jury composed of researchers, entrepreneurs and journalists. Please see the video.

    *   logo_iGEM2014.jpg The iGEM-Evry-2014 team , launched by mSSB students and hosted by iSSB, create a new biological system with environmental applications. Please see their "Sponge Patrol" project on their website. The team won a bronze medal at the final jamboree in Boston.

IronLogo.jpg * The iGEM-Evry 2013 team: "human practice" price, gold medal at the European final. It was one of the 2 French teams selected for the world final in Boston.

copy_of_IFrog.jpg *  iGEM-Evry-2012 team: two prices (best model, best human practices), gold medal at the European jamboree, selection for the world final.