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Welcome on the iSSB website

 Synthetic Biology can been defined as the design and construction of new biological parts, devices and systems (that may not exist in the natural world) or the redesign and fabrication of existing, natural biological systems for useful purposes. Its goal is to learn how to engineer and build self-organizing systems that recapitulate biological functions and show new functions with industrial applications in environment, health care, and energy.

 The Institute of Systems & Synthetic Biology (iSSB) is a mixed research unit of the University of Évry-Val-d'Essonne and CNRS, also granted by Genopole® and affiliated to U. Paris-Saclay. iSSB is structured into 4 research teams. Systems Biology integrates experimental, theoretical, and computational studies to model living systems. In this area, the MEGA team develops models and experimental methods for studying the structure, architecture, and expression of genomes. XenomeSynth-Bio and Bio-RetroSynth teams use Systems Biology models to design, build, and test new biological circuits and devices using Synthetic Biology principles.

Please download the flyer of iSSB.

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yeast image: Col Ford & Natasha de Vere

Location - contact


5 rue Henri Desbruères
Genopole Campus 1, Bât. 6

contact (at)

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37


To come, please follow Genopole access indications. On the Genopole campus, iSSB is located at 1st floor of Building 6, placed on your left (if you come by pedestrian entry) or on your right (if your come by vehicle entry).


Longitude: E 2° 27' 4''
Latitude: N 48° 37' 7''



 The iGEM-Evry 2016 team, with his project Let's PLAy! will try to produce a bioplastic ready to be used for biomedical applications and 3D printing. In order to forward their project until Boston, they are carrying a crowd funding campaign at .

  The European Experience 2016!  The teams iGEM Evry and iGEM IONIS have organized together a thrilling meeting week-end, gathering students from all Europe who came to Paris and presented their iGEM project.


  Based on publications in synthetic biology, an independent study (Nov 2015) found that iSSB ranks 3rd lab in Europe and 9th in the world, despite a comparatively small size.