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Welcome on the iSSB website

 Synthetic Biology can been defined as the design and construction of new biological parts, devices and systems (that may not exist in the natural world) or the redesign and fabrication of existing, natural biological systems for useful purposes. Its goal is to learn how to engineer and build self-organizing systems that recapitulate biological functions and show new functions with industrial applications in environment, health care, and energy.

 The Institute of Systems & Synthetic Biology (iSSB) is a mixed research unit of the University of Évry-Val-d'Essonne and CNRS, also granted by Genopole® and affiliated to U. Paris-Saclay. iSSB is structured into 4 research teams. Systems Biology integrates experimental, theoretical, and computational studies to model living systems. In this area, the MEGA team develops models and experimental methods for studying the structure, architecture, and expression of genomes. XenomeSynth-Bio and Bio-RetroSynth teams use Systems Biology models to design, build, and test new biological circuits and devices using Synthetic Biology principles.

Please download the flyer of iSSB.

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yeast image: Col Ford & Natasha de Vere

Location - contact


5 rue Henri Desbruères
Genopole Campus 1, Bât. 6

contact (at)

Phone: +33(0)1 69 47 44 30
Fax: +33(0)1 69 47 44 37


To come, please follow Genopole access indications. On the Genopole campus, iSSB is located at 1st floor of Building 6, placed on your left (if you come by pedestrian entry) or on your right (if your come by vehicle entry).


Longitude: E 2° 27' 4''
Latitude: N 48° 37' 7''



  Based on publications in synthetic biology, an independent study (Nov 2015) found that iSSB ranks 3rd lab in Europe and 9th in the world, despite a comparatively small size.

 BioSynSys 2016, June 27-29, 2016 in Bordeaux, France

"Genome Architecture in Space and Timeat ICTP, June 20-24, 2016, in Trieste, Italy


igem-Evry-2015 The iGEM-Evry 2016 team is launched by mSSB students. To learn about iGEM-Evry teams hosted by iSSB, please visit our iGEM webpage.